Sunday 19 February 2012

Introduction of Myosin II

The type of myosin present in muscle (myosin II) is a very large protein (about 500 kd) consisting of two identical heavy chains (about 200 kd each) and two pairs of light chains (about 20 kd each). Each heavy chain consists of a globular head region and a long α-helical tail. The α-helical tails of two heavy chains twist around each other in a coiled-coil structure to form a dimer, and two light chains associate with the neck of each head region to form the complete myosin II molecule.
The structure of Myosin II:
The myosin II molecule consists of two heavy chains and two pairs of light chains (called the essential and regulatory light chains). The heavy chains have globular head regions and long α-helical tails, which coil around each other to form dimers.

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